Posts by Florian J. Fintelmann, MD
New AI Tool Predicts Six-Year Lung Cancer Risk From a Single CT Scan
Lecia V. Sequist, MD, MPH, Florian J. Fintelmann, MD, and colleagues have created and validated Sybil, a convolutional neural network that requires only one low-dose CT scan to predict future lung cancer, regardless of whether visible lung nodules are present and possibly independent of the patient's smoking history.
Automated Deep Learning Accurately Assesses Muscle and Fat Tissue on Routine Chest CT
Massachusetts General Hospital researchers created a fully automated deep learning system to quantify and characterize muscle and adipose tissue on CT scans at multiple thoracic vertebral levels. The system is as accurate as human analysts on routine CT scans, regardless of intravenous contrast.
Treating Lung Metastases with Image-Guided Ablation
Image-guided ablation represents an alternative approach for patients who cannot undergo surgery or radiation due to the extent of metastatic disease or comorbidities including limited respiratory function, advanced age or prior radiation therapy.
Dr. Fintelmann is integrated into the Thoracic Cancer Team at Massachusetts General Hospital. His research focuses on improving lung cancer care with advanced imaging techniques and image-guided minimally invasive interventions.
Dr. Fintelmann studies the spectrum of lung cancer imaging manifestations ranging from early diagnosis (lung cancer screening) to advanced disease. Dr. Fintelmann is particularly interested in leveraging quantitative image analysis and machine learning tools to derive morphomic data (body composition metrics) from computed tomography exams obtained as part of routine clinical care to better stratify patients for appropriate therapies. He is part of a multi-disciplinary research team dedicated to furthering the understanding of cancer cachexia.
Dr. Fintelmann believes that lung cancer patients benefit from interventional oncology and is working on furthering the role of minimally invasive image-guided diagnostic and therapeutic procedures. Specifically, he is studying thermal ablation (cryoablation, microwave ablation) and lung biopsies. Ongoing clinical trials in collaboration with the MGH Cancer Center investigate possible synergy between immunotherapy and cryoablation in patients with advanced lung cancer and advanced melanoma (cryoimmunotherapy, cryoimmunology).