Meghan Sise, MD, is a nephrologist in the Department of Medicine at Massachusetts General Hospital. Her research is focused on determining the impact and mechanism of Hepatitis C Virus (HCV) on the progression of chronic kidney disease (CKD) through clinical and translational investigation in patients with HCV mono-infection and co-infection with HCV and human immunodeficiency virus (HIV). Sise has focused on the safety and efficacy of novel direct-acting antiviral agents for HCV in both patients with chronic kidney disease and end-stage renal disease on dialysis. She conducts clinical trials and longitudinal observational studies in these populations. Meghan Sise currently holds a faculty appointment at Massachusetts General Hospital in the Division of Nephrology with 75% of her time dedicated to research and she maintains an active clinical presence with 20% clinical and 5% teaching effort.