Posts by Jehan W. Alladina, MD
Discovering the Pathways That Lead to Allergic Asthma
Jehan Alladina, MD, and colleagues of the Division of Pulmonary and Critical Care Medicine at Massachusetts General Hospital, are using an innovative in vivo research method to study allergic asthma pathogenesis.
Plasma sST2 Provides Prognostic Information in COVID-19 Respiratory Failure
Jehan W. Alladina, MD, and Benjamin D. Medoff, MD, of the Division of Pulmonary and Critical Care Medicine, and colleagues advise that high plasma concentrations of soluble suppression of tumorigenicity-2 may signify persistent lung injury in COVID-19 respiratory failure and the need for continued ventilatory support.
BMI Not Associated With Meaningful Differences in COVID-19 Critical Illness Outcomes
Massachusetts General Hospital physicians within the Division of Pulmonary and Critical Care Medicine examine the relationship between obesity and critical illness.
Biomarker-driven Approach to Ventilator Liberation Successful for Patients With Acute Hypoxemic Respiratory Failure
Jehan Alladina, MD, and Ednan K. Bajwa, MD, of the Division of Pulmonary and Critical Care Medicine, found that serial measurement of soluble suppression of tumerogenicity-2, an inflammatory biomarker, indicates readiness for ventilator liberation better than standard physiologic measures in patients with acute hypoxemic respiratory failure.
Medical Grand Rounds: Impact of COVID-19 among Older Persons
On May 28, 2020, the 12th lecture in the Medical Grand Rounds’ COVID-19 series featured a panel of experts who discussed the impact of COVID-19 on older populations.
Respiratory Pathophysiology of Mechanically Ventilated Patients with COVID-19 Is Typical of ARDS
Massachusetts General Hospital researchers find that patients with COVID-19 respiratory failure exhibited gas exchange, respiratory system mechanics and response to prone ventilation similar to that of prior large cohorts of patients with ARDS.
Alveolar Recruitment in Patients with ARDS Related to COVID-19
In patients with acute respiratory distress syndrome related to COVID-19, care must be taken to choose the positive end-expiratory pressure that opens alveoli without over-distending the large amount of normal lung.
Managing PEEP and Recruitment
Many people are asking...how should I manage PEEP and alveolar recruitment in COVID-19 ARDS patients?
Jehan W. Alladina, MD, is a physician in the Division of Pulmonary and Critical Care Medicine at Massachusetts General Hospital and an instructor in medicine at Harvard Medical School.