Biography

The Medoff Laboratory at Massachusetts General Hospital studies the pathogenesis of pulmonary inflammation, specifically the role of T cells in mediating inflammatory lung diseases. Using genetically modified mice in various models of lung disease, as well as translational studies in humans with various lung diseases, we study mechanisms of T cell activation and function in the context of these disorders. As a result of this work, we hope to delineate some of the molecular mechanisms involved in the development of lung inflammation. In addition, we hope to reveal novel aspects of lung immune biology and potential therapeutic targets for these disorders.

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