Posts by Young-Min Kwon, MD, PhD
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Machine Learning Models Identify Patients at High Risk of Prolonged Hospital Stay After Primary THA
Tony Lin-Wei Chen, MD, PhD, Young-Min Kwon, MD, PhD, and colleagues at the Bioengineering Lab developed accurate machine learning models that identify patients at high risk of prolonged hospitalization after primary total hip arthroplasty, pinpointing risk factors that can be optimized preoperatively.
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Two-Stage Revision TJA as Salvage for Deep Infection of Periarticular Fracture Internal Fixation
Janna van den Kieboom, MD, Young-Min Kwon, MD, PhD, and colleagues at the Bioengineering Lab observed a 43% overall failure rate and 35% reinfection rate in patients who underwent two-stage revision hip/knee total joint arthroplasty as a salvage procedure for deep infection of periarticular fracture internal fixation.
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AI Accurately Identifies Both Primary and Revision Arthroplasty Implants From Plain Radiographs
Young-Min Kwon, MD, PhD, and colleagues in the Bioengineering Laboratory developed and validated a convolutional neural network that is 96% accurate or more when identifying arthroplasty implants from plain radiographs, whether primary or revision and whether implanted in the hip or knee.
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Mass General Program Encourages Diversity in Orthopedics
Mass General's Summer Research Trainee Program offers research and career development mentorship for under-represented minorities in medicine.
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Tourniquet-less Revision TKA a Viable Option for Selected Patients
Massachusetts General Hospital researchers found tourniquet-less revision total knee arthroplasty leads to increased perioperative blood loss, but not increased transfusion rates, and they linked tourniquet omission to reductions in length of stay, 30-day readmissions and overall 90-day major complications.
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U.S. Minority Groups Have Worse Outcomes Than White Patients After Revision Total Hip and Knee Joint Arthroplasty
Christian Klemt, PhD, Anand Padmanabha, MD, Young-Min Kwon, MD, PhD, and colleagues have determined that utilization of revision total hip and knee joint arthroplasty (TJA) in racial/ethnic minorities is worse than for primary TJA, and a number of post-revision outcomes are significantly worse than for white patients.
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Dual Mobility Implants Viable Alternative for Revision THA in Some Patients
Researchers in Massachusetts General Hospital's Bioengineering Lab found that among patients undergoing revision THA who had severe tissue necrosis and abductor muscle deficiency, none who received a dual mobility implant experienced dislocation, versus 16% of those who received conventional liners.
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Timing of Lumbar Spinal Fusion Relative to Revision Total Hip Arthroplasty Affects Complications
Postoperative instability rates are lower when patients undergo revision total hip arthroplasty before lumbar spinal fusion than when the order is reversed, according to a study by Christian Klemt, PhD, Young-Min Kwon, PhD, MD, and colleagues in the Bioengineering Lab of the Department of Orthopaedics.
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New Cruciate-Retaining TKA Implant Does Not Fully Restore In Vivo Articular Contact Kinematics During Strenuous Activities
A new cruciate-retaining implant for TKA has asymmetric tibial polyethylene bearing geometry to improve outcomes. However, Christian Klemt, PhD, Young-Min Kwon, MD, PhD, and colleagues in the Bioengineering Lab observed deficiencies when patients performed strenuous activities postoperatively.
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Smoking, Drinking Increase Risks of Poor Outcomes After Revision Total Hip and Knee Joint Arthroplasty
Smokers and drinkers have markedly higher risks of in-hospital complications, major postdischarge complications and re-revision for periprosthetic joint infection than nonusers, and people who both smoke and drink (concurrent users) have the worst outcomes of all.
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Spinal Anesthesia Is a Viable Option for Revision THA in Selected Patients
When spinal anesthesia was administered during revision total hip arthroplasty, perioperative blood loss, inhospital complications and length of stay were significantly lower than in a propensity-matched cohort that received general anesthesia.
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Optimal Synovial Marker Thresholds for Diagnosis of Infection Differ in Taper Corrosion of Metal-on-Polyethylene THA
When patients have adverse local tissue reactions (ALTR) due to head-neck taper corrosion of metal-on-polyethylene (MoP) hip implants, synovial marker thresholds for diagnosing periprosthetic joint infection are lower than the reported ALTRs associated with metal-on-metal hip implants and MoP implants without ALTRs.
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Isolated Bearing Exchange a Viable Surgical Option for THA Failure Due to Osteolysis
Isolated bearing exchange with allogenic bone grafting is an effective treatment option when failure of total hip arthroplasty is due to periprosthetic osteolysis surrounding well-fixed acetabular and/or femoral components.
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ESR/CRP Ratio Identifies Reinfection Risk After Treatment of Chronic Prosthetic Joint Infection
The preoperative ratio of routinely available erythrocyte sedimentation rate and C-reactive protein identified which patients with chronic prosthetic joint infection were at increased risk of postoperative reinfection after debridement, antibiotics and implant retention.
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Single Axis Radius Posterior-Substituting Knee Prosthesis Does Not Fully Restore Joint Biomechanics
A recently introduced-design of posterior-substituting, high-flexion knee prosthesis did not fully replicate the posterior femoral translation and ligament isometry of a healthy knee during in vitro robotic analysis.
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High Rate of Early Complications When THA Revised Due to Adverse Local Tissue Reactions
Massachusetts General Hospital surgeons noted high complication rates and frequent need for re-revision following revision surgery of both metal-on-metal and metal-on-polyethylene total hip implants with adverse local tissue reactions.
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Preoperative Opioid Use Negatively Affects Patient-reported Outcomes of Total Hip Arthroplasty
Preoperative opioid use was associated with poorer patient-reported outcomes after total hip arthroplasty as well as longer hospital stays and higher rates of discharge to a rehabilitation facility.
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Bicruciate-retaining TKA Does Not Restore Articular Contact Behavior During Gait
Orthopedic surgeons at Massachusetts General Hospital became the first to investigate how the recently introduced bicruciate-retaining total knee arthroplasty affects in vivo kinematics, articular contact position and pivot point location during gait.
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Gender Influences Gait Asymmetry After Bicruciate-Retaining TKA
Gender differences have been reported to influence the functioning of the anterior cruciate ligament in native knees. What happens to gait when the ACL is preserved in patients with total knee arthroplasty? Orthopedic surgeons at Massachusetts General Hospital were the first to explore this question.
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Bi-Cruciate Retaining TKA Does Not Restore Native Joint Motion During Functionally Strenuous Activities
Patients implanted with a modern system for bi-cruciate retaining total knee arthroplasty did not exhibit full replication of the articular contact kinematics of the native knee during functionally strenuous high-flexion activities, orthopedic surgeons at Massachusetts General Hospital report.
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Research Advances from Mass General Orthopaedics
Researchers from the Department of Orthopaedics discuss the clinical and translational work they are doing at Massachusetts General Hospital.
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Understanding the Multiple Aspects of Head-Neck Taper Corrosion in Metal-on-Polyethylene Total Hip Arthroplasty
Head-neck taper corrosion is an infrequent but emerging serious complication of metal-on-polyethylene total hip arthroplasty (THA) and failure to diagnose adverse local tissue reactions (ALTR) early can lead to revision surgeries and implant failure.
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Use of Opioids Before Knee Replacement Negatively Affects Post-op Quality of Life
Opioid use prior to total knee arthroplasty is associated with inferior health-related quality of life after surgery.
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Bioengineering Laboratory: Visualizing Patient-Specific Kinematics for Hip and Knee Arthroplasty
Massachusetts General Hospital's Bioengineering Laboratory is currently utilizing an innovative, non-invasive imaging tool that enables a visualization of the kinematics of hip and knee replacement implants in patients while they perform functional activities.
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After THA, Metal Ion Measurement and MRI Recommended to Evaluate Suspected Head–Neck Taper Corrosion
Mass General surgeons recommend prompt diagnostic testing for head–neck taper corrosion after metal-on-polyethylene THA because early complications are common.
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Multiple Intra-articular Steroid Hip Injections Bring Greater Infection Risk
Multiple intra-articular steroid hip injections versus one injection bring far greater risk of periprosthetic joint infections for total hip arthroplasty patients.
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Taper Corrosion in Total Hip Arthroplasty
Taper corrosion-related ALTR is a rare complication of THA. A systematic evaluation may ensure early diagnosis to improve revision-surgery outcomes.
Biography
Young-Min Kwon, MD, PhD, FRACS, FRCS, earned his MD with Honors from the University of Sydney, Australia and completed his orthopaedic residency at Concord Repatriation General Hospital, Sydney. Dr. Kwon completed his Fellowship in Adult Reconstructive Surgery at MGH/Harvard Medical School. He then completed a second Hip Reconstruction Fellowship at the University Hospital Balgrist, Zurich, Switzerland. Dr. Kwon also earned a PhD from the University of Oxford, England. He is Board Certified in Orthopaedic Surgery with the American Board of Orthopaedic Surgery (ABOS), the Royal College of Surgeons of England (FRCS) and the Royal Australian College of Surgeons (FRACS).
Dr. Kwon is Director of the Adult Reconstructive Surgery Fellowship, the Bioengineering Laboratory, as well as The Center for Metal-on-Metal Hip & Tribocorrosion. He has been the recipient of numerous awards and honors, including the Sir John Irvine Hunter Prize in conjunction with the title of Prosector, the AOA Travelling Fellowship Award, the Royal College of Surgeon's Traveling Fellowship Award, the New Investigator Recognition Award from the Orthopaedic Research Society, the Kappa Delta Award from the American Academy of Orthopaedic Surgeons (AAOS) and the John Charnley Award from the US Hip Society.
Orthopaedic Care at Mass General
At Mass General, our world-class physicians and surgeons treat the full spectrum of musculoskeletal conditions throughout the body, from sprains and strains on the athletic field to carpal tunnel syndrome. Our team offers innovative, research-based treatments that range from limb-saving oncological procedures to complex spinal reconstruction.