Posts by Akl C. Fahed, MD, MPH
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New Approach Uses Public Genomics Data to Predict Risk of Cardiometabolic Disease in Non-European Populations
Researchers at Massachusetts General Hospital and two hospitals in Saudi Arabia developed a pragmatic approach to optimizing European-derived polygenic risk scores for non-European populations using published genome-wide association data. They verified the clinical utility of scores for Arab people.
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Assessing Heart Attack Risk With Genetics: Q&A With Akl C. Fahed, MD, MPH
Genome interpretation can augment our ability to interpret risk of heart attacks. Akl C. Fahed, MD, MPH, discusses a recent study that successfully implemented state-of-the-art genome interpretation for heart attack risk and showed that it is understandable and beneficial for people.
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Healthy Lifestyle Linked to Less Risk of CAD in Patients With Familial Hypercholesterolemia
Akl C. Fahed, MD, MPH, Amit V. Khera, MD, MSc, and colleagues found that carriers of familial hypercholesterolemia gene variants who followed healthy lifestyle practices had minimal change in LDL cholesterol yet were at 86% less risk of coronary artery disease than carriers whose lifestyle was unhealthy.
Biography
Akl C. Fahed, MD, MPH is an interventional cardiologist at Massachusetts General Hospital, physician-scientist at the Massachusetts General Hospital Cardiovascular Research Center, and an instructor in medicine at Harvard Medical School.