Dr. Powe received an A.B. degree cum laude from Harvard College and an M.D. degree from Harvard Medical School magna cum laude. She completed a residency in internal medicine at Brigham and Women's Hospital, where she also served as Chief Medical Resident. Dr. Powe completed her endocrinology fellowship at Massachusetts General Hospital.
Dr. Powe specializes in treating endocrine disorders, such as diabetes, in pregnancy. She co-directs the MGH Diabetes in Pregnancy Program, a collaboration between the Diabetes Unit and the Maternal Fetal Medicine division.
Dr. Powe conducts clinical research on the genetics and physiology of metabolic disease in pregnancy.