Posts by Christian Lacks Lino Cardenas, PhD, PharmD
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Newly Identified Genes Linked to Coronary Artery Calcification
Hanna Barnes, MD, Christian Lino Cardenas, PhD, PharmD, Rajeev Malhotra, MD, and colleagues add to the understanding of the genetic basis of coronary artery calcification by identifying 43 candidate genes at 11 chromosomal locations and demonstrating effects on cellular reprogramming leading to vascular calcification.
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Rare Smooth Muscle Disorder Traced to a Single Mutation in a Non-coding Gene
In the first case of its kind, Massachusetts General Hospital researchers detected a monogenetic vascular disease caused by a mutation in a non–protein-encoding gene. They linked multisystemic smooth muscle dysfunction syndrome to a single-nucleotide variant in MIR145.
Biography
Christian Lacks Lino Cardenas, PhD, PharmD, is an instructor in medicine in the Cardiovascular Research Center at Massachusetts General Hospital and at Harvard Medical School.