Posts by James J. Moon, PhD
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T Cells With Known Specificity Used to Determine the Treg Response in Lung Injury
Daniel S. Shin, MD, PhD, James J. Moon, PhD, and colleagues have discovered that in response to acute lung injury, self-antigen-specific CD4+ T cells have a strong propensity to polarize toward a regulatory function that limits further damage and the possibility of autoimmunity.
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Efficient Early Immune Control of COVID-19 Predicts Favorable Long-term Adaptive Immunity
In blood samples from patients who recovered from the first wave of SARS-CoV-2 infection, Massachusetts General Hospital researchers found some CD4+ T cell subsets were more common with milder disease. This response persisted for several months, potentially giving the immune system an advantage for subsequent exposure.
Biography
James J. Moon, PhD, is a principal investigator in the Center for Immunology and Inflammatory Diseases at Massachusetts General Hospital and an assistant professor of medicine at Harvard Medical School.
Rheumatology, Allergy and Immunology
The Division of Rheumatology, Allergy and Immunology at Massachusetts General Hospital provides leading-edge treatment and transformative care to patients with rheumatic disease and autoimmune conditions.