Posts by Robert Manguso, PhD
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Novel Strategy Proposed To Enhanced Treatment of Cholangiocarcinoma With IDH1 Mutations
Meng-Ju Wu, PhD, Nabeel Bardeesy, PhD, Robert Manguso PhD, and colleagues found in a mouse model of cholangiocarcinoma that immune function and the interferon-gamma/TET2 axis are essential for response to mutant IDH1 inhibitors, and they suggest a novel strategy for boosting the efficacy of these inhibitors.
Biography
Robert Manguso, PhD, is principal investigator of the Manguso Lab in the Massachusetts General Hospital Cancer Center and an assistant professor of medicine at Harvard Medical School.
Mass General Cancer Center
An integral part of one of the world’s most distinguished academic medical centers, the Massachusetts General Hospital Cancer Center is among the leading cancer care providers in the United States.
