Posts by Jia Yin, MD, PhD, MPH
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The Neuropeptide Alpha-Melanocyte–stimulating Hormone Prevents Persistent Corneal Edema After Injury
Reza Dana, MD, MSc, MPH; Jia Yin, MD, PhD, MPH; Ula V. Jurkunas, MD; and colleagues have discovered a critical role for neuropeptides in maintenance of corneal endothelial cells and potential therapeutic applications for α-melanocyte–stimulating hormone after corneal injury or intraocular surgery.
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Alpha-Melanocyte–stimulating Hormone Is Critical to Corneal Graft Survival
Researchers at Mass Eye and Ear have differentiated the cytoprotective action of alpha-melanocyte–stimulating hormone (alpha-MSH) on corneal graft tissue from its effect on the graft recipient's immune response by alternating use of transgenic mice with a truncated alpha-MSH receptor as the graft donor or host.
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Incidence of Ocular Burns Increasing in U.S.
Ophthalmologists at Massachusetts Eye and Ear/Massachusetts General Hospital found in a U.S. ophthalmology registry study that the incidence of ocular burns increased 20% between 2013 and 2017, and women and men were affected equally.
Biography
Dr. Yin is a full-time member of the Mass Eye and Ear Cornea and Refractive Surgery Service, and specializes in corneal and external diseases, cataract surgery, corneal transplantation, and refractive surgery.
Dr. Yin conducts basic and clinical research in corneal and ocular surface diseases. Her basic scientific research focuses on the understanding of corneal angiogenesis, innervation, inflammation, and wound healing. Her clinic research focuses on improving the diagnosis and treatment of corneal diseases, limbal stem cell deficiency, dry eye syndrome, and other ocular surface diseases.
Mass Eye and Ear/Mass General Ophthalmology
An international center for ophthalmology treatment and research, Mass Eye and Ear/Massachusetts General Hospital is the primary teaching hospital of Harvard Medical School’s Department of Ophthalmology, and is consistently recognized as one of the nation’s top hospitals for eye care. Led by Chief and Chair Joan W. Miller, MD, the department provides seamless access to the most innovative care available anywhere in the world.
