Posts by Suk-tak Chan, PhD
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Novel Evaluation of Cerebrovascular Response in Chronic Mild Traumatic Brain Injury
Radiologists and neurologists at Massachusetts General Hospital have shown that an O2-CO2 exchange ratio is more useful than change in partial pressure of carbon dioxide when using functional MRI to assess cerebrovascular response to a breath-hold challenge in patients with chronic mild traumatic brain injury.
Biography
Suk-tak Chan, PhD, received her PhD in Radiography/Ultrasound from Hong Kong Polytechnic University. Dr. Chan joined the Athinoula A. Martinos Center for Biomedical Imaging at MGH in 2010 as an instructor. Her current research focuses on imaging of cerebrovascular responses using ultrasound and MRI. She uses natural breathing/gaseous challenge to measure cerebrovascular responses in healthy subjects, patients with episodic migraine, traumatic brain injury, Huntington’s disease, atrial fibrillation and chronic fatigue syndrome. She has developed a robust physiological model for the assessment of cerebrovascular reactivity under brief breath hold challenge. Her model has been tested on patients to localize subtle cerebrovascular changes for disease diagnosis and monitoring of disease progression.
