Posts by Dejan Juric, MD
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Cell-Free DNA Assay Can Identify Microsatellite Instability–High Status in Advanced Breast Cancer
Neelima Vidula, MD, Dejan Juric, MD, Aditya Bardia, MD, MPH and colleagues from multiple centers in the U.S. have demonstrated that plasma-based genotyping ("liquid biopsy") can identify microsatellite instability–high status in patients with metastatic breast cancer.
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PTEN Loss Mediates Cross-Resistance to CDK4/6 and PI3Ka Inhibitors in Breast Cancer
Dejan Juric, MD and colleagues have provided proof of concept that a single genetic event—in this study, loss of PTEN expression in estrogen receptor–positive, HER2-negative advanced breast cancer—can cause cross-resistance to multiple targeted therapies and affect subsequent lines of treatment.
