Posts by Jacob M. Hooker, PhD
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Review: The Role of Histone Deacetylases in Autism Spectrum Disorder
Massachusetts General Hospital researchers recently reviewed research on relationships between autism spectrum disorder (ASD) and histone deacetylases (HDACs), enzymes that can suppress gene transcription. Animal research and preliminary human evidence show HDAC inhibition might alleviate ASD symptoms.
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Histone Deacetylases Appear to Have Pathophysiologic Role in Bipolar Disorder
Massachusetts General Hospital researchers have reported the first in vivo human evidence of a role for histone deacetylases in the pathophysiology of bipolar disorder as well as in two of its hallmark clinical features, emotional dysregulation and attention deficits.
Mass General Imaging
For over 100 years, the Department of Radiology at Massachusetts General Hospital has pioneered imaging technology to improve human health. Today, our researchers develop powerful new ways to diagnose and treat many diseases. From the lab to the clinic, our community of radiologists and researchers brings advances directly to our patients.