Posts by James R. Stone, MD, PhD
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Infection of the Heart Commonly Seen at Autopsy of Patients Who Died of COVID-19
In the most detailed study to date, Mayara Bearse, MD, and James R. Stone, MD, PhD, of the Department of Pathology, and colleagues, cardiac infection by SARS-CoV-2 was evident in 73% of autopsies of patients who died of COVID-19 and was linked to differences in clinical features and treatment.
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Histopathology of COVID-19 Is Typical of Acute Respiratory Distress Syndrome
By reviewing autopsy and biopsy studies, Massachusetts General Hospital researchers have shown that COVID-19 manifests principally as diffuse alveolar damage, the histopathologic pattern typically associated with acute respiratory distress syndrome.
Biography
Dr. Stone has published extensively on cardiovascular diseases including atherosclerosis, vasculitis, amyloidosis, and cardiomyopathies. He is a founding co-chair of the Standards and Definitions Committee of the Society for Cardiovascular Pathology, and directs the core laboratory of an NIH-funded multi-center study of cardiac allograft rejection. He is a member of the Center for Systems Biology, where his laboratory studies basic mechanisms relating to the cellular and molecular biology of cardiovascular diseases