Posts by Josep M. Mercader, PhD
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Newly Identified Genetic Variant Has Substantial Effect on Risk of Type 2 Diabetes
Most genome-wide association studies (GWAS) are likely to miss variants with recessive effects. In a large recessive-model GWAS, Massachusetts General Hospital researchers identified a novel locus associated with 2.56 greater risk of type 2 diabetes in homozygous carriers that also had substantial effects on lipids.
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BMI Is a Causal Risk Factor for COVID-19 Susceptibility, Severity
Massachusetts General Hospital researchers tested 17 cardiometabolic diseases and traits and found that body mass index was causally associated with developing COVID-19 and being hospitalized for the disease.