James F. Markmann MD, PhD, is the Chief of the Division of Transplant Surgery and Director of Clinical Operations at the Transplant Center at Massachusetts General Hospital, and the Claude Welch Professor of Surgery at Harvard Medical School. He specializes in liver, kidney, pancreas and islet transplantation as well as hemodialysis access surgery. He is active in numerous societies, editorial boards and organizations and is currently secretary of the International Pancreas and Islet Transplant Association and Councilor of the American Society of Transplant Surgeons. He has published more than 300 scientific papers over the last 30 years, most in the area of immune tolerance and pancreas and islet transplantation and has held continuous NIH R01 funding for >15 years. His current research interests include: 1) understanding the mechanism of action and therapeutic potential of regulatory B cells, 2) exploring the potential of ex vivo liver perfusion to improve marginal organ function, and 3) clinical trials in transplantation tolerance and pancreatic islet transplantation.