Posts by Samuel D. Rabkin, PhD
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Review: Oncolytic Herpes Simplex Viruses for Treatment of Glioma
Kimia Kardani, PhD, Judit Sánchez Gil, PhD, and Samuel D. Rabkin, PhD, describe in a review how herpes simplex viruses can be engineered to treat cancer safely, and they discuss the current state of oncolytic virus therapy for glioblastoma.
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Combined Blockade of ATR and PARP Effective Against Glioblastoma in Mice
The combination of olaparib and an ATR inhibitor was effective against glioblastoma in mice, providing a much-needed therapeutic breakthrough for this deadly disease.
Biography
Samuel Rabkin, PhD, is the Thomas A. Pappas Professor in Neurosciences and Professor of Neurosurgery (Microbiology) at Harvard Medical School, Boston MA, and Virologist in Neurosurgery in the Brain Tumor Research Center at Massachusetts General Hospital, Boston. Dr. Rabkin's lab has focused on the development of oncolytic herpes simplex virus (oHSV) for cancer therapy, including the first oHSV to enter clinical trial in the US and oHSV immunovirotherapy strategies and combinations for glioblastoma.
Neuroscience Care at Mass General
Through a combination of unmatched expertise, creativity and compassion, Mass General Neuroscience relentlessly advances the fields of Neurosurgery, Neurology and Psychiatry to unleash our patients’ potential.