Posts by Lydia Shook, MD
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Sex-specific Impact of Maternal Obesity on Fetal Placental Macrophages and Cord Blood Triglycerides
LydiaL. Shook, MD, Andrea G. Edlow, MD, MSc, and colleagues observed that maternal obesity was more immune-activating in the male than female placenta. They also observed sexual dimorphism in placental lipid transfer. These findings may explain sex differences in cardiometabolic disease risk in obesity-exposed offspring.
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COVID-19 Vaccination During Pregnancy Produces Durable Antibodies in Young Infants
Lydia L. Shook, MD, Andrea G. Edlow, MD, MSc, and colleagues found that at age six months, infants born to mothers vaccinated against COVID-19 during pregnancy were significantly more likely to have detectable antibodies to the SARS-CoV-2 spike protein than infants whose mothers became infected with SARS-CoV-2 during pregnancy.
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Review: Mechanisms of Maternal Obesity with Neuromorbidity in Offspring
Studies are uncovering how prenatal and lactational exposure to maternal obesity leads to neurodevelopmental and psychiatric disorders in offspring.
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Review: Cardiometabolic Effects of Exposure to Maternal Obesity
Perinatal exposure to maternal obesity has lasting adverse cardiometabolic effects on children, including increased risk of cardiovascular mortality in adulthood.
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Percutaneous Valve Replacement Therapy Sometimes an Option During Pregnancy
According to Massachusetts General Hospital clinicians, percutaneous balloon mitral valvuloplasty is now the treatment of choice when mitral valve repair is indicated during pregnancy, and catheter-based procedures are being tried for treatment of aortic stenosis in pregnant women.
Biography
Lydia Shook, MD, is a maternal-fetal medicine specialist in the Department of Obstetrics and Gynecology and an investigator in the Vincent Center for Reproductive Biology at Massachusetts General Hospital.
Obstetrics & Gynecology Care at Mass General
The Mass General Department of Obstetrics & Gynecology offers the highest level of care to women. Our clinical and research team is a leader in advancing treatments for gynecologic cancers, menopause, high-risk obstetrics, infertility and urogynecology.