Posts by Eloise Hudry, PhD
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Review: Direct Gene Transfer to the Nervous System Now a Clinical Reality
After decades of development, adeno-associated virus gene transfer is showing promise for permanent or long-lasting correction of neurologic disorders.
Biography
Eloise Hudry, PhD, is Assistant Professor of Neurology at Harvard Medical School and has been working at the MassGeneral Institute of Neurodegenerative Diseases (MIND) since 2009. She is currently a group leader for a small team of 5 people. MIND was founded with the mission to translate laboratory discoveries into finding new drug candidates to prevent, treat and cure Alzheimer’s, ALS, Huntington’s, Parkinson’s and other neurodegenerative diseases. Originally from France, she received a PhD in Neurosciences in Paris (University Rene Descartes Paris 5, Pharmaceutical Science), before coming to the United States for a postdoctoral fellowship at Harvard Medical School. Her PhD work was focused on developing new gene therapy approaches to treat monogenic neurodegenerative diseases such as Adrenoleukodystrophy, Metachromatic dystrophy, etc. She mainly worked on mouse models but her research activity has always been closely connected to the clinical and medical world, and she greatly appreciates the translational aspect of her work. Eloise joined the laboratory of Professor Bradley Hyman at MGH-Harvard in 2009, primarily working on trying to understand the molecular processes and signaling pathways leading to neurodegeneration in Alzheimer's disease. Her research projects involved skills in molecular biology, biochemistry, surgery, immunohistology, etc.