Posts by Thurman M. Wheeler, MD
-
Novel Mouse Model Allows Rapid Evaluation of Candidate Drugs for Muscular Dystrophy
Neurologists at Massachusetts General Hospital have created a bitransgenic mouse model that expresses an alternative splicing reporter of myotonic dystrophy type 1 and enables rapid, noninvasive estimation of the pharmacodynamics of potential new drugs.
-
Extracellular RNA in Urine Is a Source of Biomarkers for Muscular Dystrophy
Researchers at Massachusetts General Hospital are the first to show that mRNA splicing patterns in urine present a rich source of personalized biomarkers for muscular dystrophy—with implications for monitoring other systemic diseases.
Neuroscience Care at Mass General
Through a combination of unmatched expertise, creativity and compassion, Mass General Neuroscience relentlessly advances the fields of Neurosurgery, Neurology and Psychiatry to unleash our patients’ potential.