Posts by Ravi V. Shah, MD
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Metabolic Cost of Exercise Initiation Higher in HFpEF
Ravi V. Shah, MD, and Gregory D. Lewis, MD, of the Corrigan Minehan Heart Center, and colleagues have defined a new measure, "internal work"—the metabolic cost of initiating movement—that may direct noncardiac therapy for exercise intolerance in patients who have heart failure with preserved ejection fraction.
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Acute Exercise Dramatically Changes Metabolite Levels in Middle-aged Adults
Metabolic changes in response to cardiopulmonary exercise testing were part of pathways central to cardiometabolic health, cardiovascular disease and long-term outcome in middle-aged adults.
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Caution Urged in Using Polygenic Risk Scores to Predict Obesity
In the U.S.-based CARDIA study, BMI in young adulthood had more precision as a predictor of BMI in midlife than a polygenic risk score.
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Specific microRNAs Linked to Post-MI Remodeling
By studying a large cohort of patients who had cardiac MRI after myocardial infarction, scientists at Massachusetts General have demonstrated the association of microRNAs with specific features of left ventricular remodeling, suggesting it may someday be possible to pinpoint early biomarkers of heart failure.
Biography
Ravi Shah, MD, is assistant professor of Medicine at Harvard Medical School and a member of the heart failure/transplant section at Massachusetts General Hospital. He is a clinical-translational scientist focusing on the intersection between cardiometabolic disease, prevention, and heart failure. His major research interests have encompassed studies of epigenetic mediators of cardiometabolic disease (focused on non-coding RNA in heart failure and metabolism) and large-scale metabolite profiling in human cohort studies. His studies involve small human deep phenotyping as well as large epidemiological cohort studies and validations in small animal and cellular studies.
Cardiovascular Care at Mass General
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