Posts by Doo Yeon Kim, PhD
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Alzheimer’s in a Dish Model Replicates Pathology, Including Inflammation
A Mass General research team has built on their previous development of a system that fully replicates the pathology behind Alzheimer’s disease to now include inflammation
Biography
Doo Yeon Kim studies pathogenic mechanisms of Alzheimer’s disease (AD) using both cellular and animal models. He and his team developed a three-dimensional (3D) human neural cell culture model of AD, which recapitulated key aspects of AD pathology including ß-amyloid aggregation and ß-amyloid-driven tau pathology. Dr. Kim’s lab also studies how Alzheimer’s beta-secretase, BACE1, regulates synaptic and axonal ion channel trafficking using cellular and mouse models.
Doo Yeon is an Assistant Professor of Neurology at Harvard Medical School, Assistant in Neurology in the Genetics and Aging Research Unit at MIND. He received his Ph.D. at Korea Advanced Institute of Science and Technology (KAIST), South Korea. He started his postgraduate work at the Brain Disease Research Center, Ajou University Medical School, South Korea, and completed his postdoctoratal studies in Dr. Dora M. Kovacs’ laboratory at Massachusetts General Hospital, where he was appointed Assistant Professor in 2009. He was awarded a fellowship from the John Douglas French Alzheimer's Foundation in 2004.