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Minimally Invasive and Novel Therapeutics 2022

The Minimally Invasive and Novel Therapeutics (MINT) In Foregut Disease continuing medical education (CME) event, taking place from September 29-October 1, 2022, seeks to equip clinicians with knowledge of the latest physiologic tools needed to diagnose and treat benign foregut disease, and to teach them how different treatment options fit within the paradigm of overall foregut disease.

Course Overview

The Minimally Invasive and Novel Therapeutics (MINT) continuing medical education (CME) event, taking place from September 29 – October 1, 2022, seeks to equip clinicians with advanced technical knowledge of the latest surgical and endoscopic procedures needed to diagnose and treat foregut disease including abdominal wall hernias. We further hope to foster ongoing collaboration between gastroenterologists and surgeons to optimize the multidisciplinary care of patients with foregut digestive disease.

This event will be both in-person, with an optional hands-on component, and live streamed for the benefit of those who cannot attend in person.

This is a Harvard Medical School-accredited course hosted in partnership with the Swallowing, Heartburn, Esophageal Disease (SHED) Program at Massachusetts General Hospital and the Heartburn and Reflux Program at Newton-Wellesley Hospital.

Click here to register for the course.

Course Background and Description

The management of benign foregut disease continues to evolve. New physiologic tests and novel surgical and endoluminal approaches have greatly improved outcomes for patients. The published literature surrounding these therapies continues to evolve. However, this cadence can make it difficult for the busy practitioner to keep up with the latest information, resulting in a practice gap. Additionally, most surgical and gastroenterological training programs do not provide significant exposure to foregut disease management, and thus practicing physicians may not be equipped to offer the latest therapies to their patients.

In an effort to close these gaps, the MINT CME seeks to provide practicing physicians and fellows with education and training in the latest therapies with a focus on video-based technical skills.

Learning Objectives

Upon completion of the MINT CME, clinicians can expect to be able to:

  • Apply new knowledge in the management of patients with reflux and swallowing disorders
  • Develop treatment strategies based on current evidence and expert-opinion
  • Compare and contrast standard-of-care management with cutting-edge treatments

Hands-On Skills Training Workshop

This course will host an optional hands-on skills training session where physicians will have the opportunity to practice novel skills under the directorship of experts in the field. This training session will include stations dedicated to:

  • The Da Vinci Robot
  • Peroral endoscopic myotomy (POEM)
  • Per-oral pyloromyotomy (POP)
  • Endoscopic mucosal resection and radiofrequency ablation (RFA)
  • Esophageal stenting and suturing
  • transoral incisionless fundoplication (TIF)
  • Manometry and EndoFLIP

APP Session

Advanced practice providers (APPs) such as nurse practitioners and physician assistants are essential to providing quality patient care in foregut disease. Two Mass General APPs, Alexandra Maltby, PA-C, and Priyanca Waghmarae, PA-C, will host a dedicated didactic session for APPs in the field with the goal of furthering education and understanding of foregut disease and treatments, and promoting a collaborative approach to patient care.

Target Audience

This course is targeted to gastroenterologists, surgeons, nurse practitioners, physician assistants, pharmacists, nurses and dietitians. This course may also be of interest to physicians who practice in primary care.


Thursday, September 29, 2022

Start Time End Time Session Name
8:00 8:05 Introduction and welcome
8:05 8:10 Challenging esophageal endoscopy
    Esophageal stricture management
8:10 8:20 Eosinophilic esophagitis (EoE) dilation live (video and discussion)
8:20 8:30 Anastomotic stricture-balloon (video and discussion)
8:30 8:40 Advanced stricture management strategies (video and discussion)
8:40 8:50 Panel discussion
8:50 9:05 Approach to the refractory stricture
9:05 9:20 Discussion with panel
9:20 9:30 Break
    Barrett's and early esophageal cancer
9:30 9:40 Radiofrequency ablation (video and discussion)
9:40 9:50 Esophageal endoscopic mucosal resection (EMR) band assisted (video and discussion)
9:50 10:00 Cryo therapy (video and discussion)
10:00 10:10 Endoscopic submucosal dissection (ESD) esophageal nodule (video and discussion)
10:10 10:20 Panel discussion
10:20 10:50 Keynote Address: Current status of diagnostic testing for Barrett's esophagus and dysplasia
10:50 11:00 Break
11:00 11:05 Complex esophageal surgery and challenges
11:05 11:30 Foregut complications after bariatric surgery
11:30 11:55 Anti-reflux surgery in obesity (video and discussion)
11:55 12:20 Closing a large hiatus (video and discussion)
12:20 12:45 Robotic heller myotomy with intraoperative endoflip (video and discussion)
12:45 1:10 Giant paraesophageal hernia (video and discussion)
1:10 1:15 Wrap-up
1:15 2:00 Break
2:00 5:30 Hands-on skills session (rotating stations)
    Endoscopic suturing
    EMR and RFA station
    Per-oral pyloromyotomy (POP)/per-oral endoscopic myotomy (POEM)
    Endoscopic stenting
2:00 5:15 Advanced practice provider session (all are welcome)
2:00 2:05 Welcome
2:05 2:20 A to Zenkers: diagnosis and management
2:20 2:40 Case-based approach to the workup and management of patient's with EoE
2:40 2:55 Counseling patients on dietary modifications for EoE
2:55 3:05 Break
3:05 3:25 My cough is uncontrolled reflux—approach to workup and management
3:25 3:45 Postoperative dysphagia in the anti-reflux surgery patient
3:45 3:55 Rapid-fire board questions
3:55 4:05 Break
4:05 4:25 Refractory gastroesophageal reflux disease (GERD)
4:25 4:45 Post-operative complications after POP and POEM
4:45 5:05 Esophageal stents and complications
5:05 5:15 Wrap-up and questions
5:30 8:00 Cocktail reception

Friday, September 30, 2022

Start Time End Time Session Name
8:00 8:05 Welcome back
8:05 8:10 Endoscopic myotomies—learning your Z,E,G's
8:10 8:25 Zenker rigid myotomy (video and discussion)
8:25 8:40 Zenker's diverticulum-POEM (video and discussion)
8:40 8:55 POP (video and discussion)
8:55 9:10 POEM—anterior/posterior (video and discussion)
9:10 9:20 Break
    The complications
9:20 9:40 Gastroparesis after esophagectomy
9:40 10:00 Leak after POEM
10:00 10:20 Rapid fire endo complications (perforation, bleed, stent)
10:20 10:40 Dysphagia after fundoplication
10:40 11:00 Break
11:00 11:05 Anti-reflux surgery-technical challenges
11:05 11:20 Transoral incisionless fundoplication (TIF) (video and discussion)
11:20 11:35 Esophageal lengthening (Collis)
11:35 11:50 Complex redo fundoplication (video and discussion)
11:50 12:00 Discussion, tips and tricks
12:00 1:15 Break
1:15 5:30 Hands-on skills session (rotating stations)
    Robot (anti-reflux, abdominal wall reconstruction)
    Manometry and endoflip

Saturday, October 1, 2022

Start Time End Time Session
8:00 8:05 Introduction and welcome back
8:05 8:10 MINT international
8:10 9:10 Dr. Amol Bapaye and foundation for research and education in endoscopy
9:10 9:20 Break
9:20 10:50 Dr. B Ramana and abdominal wall reconstruction
10:50 11:50 Dr. Enrique de Madaria of the Spanish Association of Gastroenterology
11:50 12:00 Break
12:00 12:30 Surgical keynote
12:30 1:00 Wrap-up and questions

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Course Directors

Charudutt Paranjape, MD, MBBS, FACS

Associate Chair, Education, Mass General Brigham/Newton-Wellesley Hospital
Chief, General Surgery and Acute Care Surgery, Mass General Brigham/Newton-Wellesley Hospital
Surgical Director, Heartburn and Reflux Program, Mass General Brigham/Newton-Wellesley Hospital
Trauma, Acute Care and Critical Care Surgeon, Massachusetts General Hospital
Assistant Professor, Harvard Medical School

About Dr. Paranjape
Charudutt Paranjape, MD, MBBS, received his surgical training in India and in the United States. After completing his fellowship training at Harvard Medical School/Beth Israel Deaconess Medical Center in Boston, he worked as an attending physician at Cleveland Clinic Akron General where he formed its acute care surgery program and served as the medical director. In 2009, he founded Cleveland Clinic Akron General’s Heartburn Center where he built a comprehensive state-of-the-art multidisciplinary program.

Today, Dr. Paranjape leads the Division of General Surgery as well as Acute Care Surgery at Mass General Brigham, Newton-Wellesley Hospital, and serves as the associate chair of education. Since joining, Dr. Paranjape has launched the Newton-Wellesley Heartburn and Reflux Program, a unique multidisciplinary program involving surgeons, gastroenterologists, dietitians and advanced practice providers. He is also an active member of the Swallowing, Heartburn and Esophageal Disease (SHED) Center at Massachusetts General Hospital. Dr. Paranjape serves on many national committees including The Society for Surgery of the Alimentary Tract, Society of American Gastrointestinal and Endoscopic Surgeons.

Kumar Krishnan, MD

Director, Endoscopic Innovation, Technology, and Education for Gastroenterology, Massachusetts General Hospital
Assistant Professor of Medicine, Harvard Medical School

About Dr. Krishnan
Kumar Krishnan, MD, received his Bachelor of Science in Biochemistry with honors from the University of Arizona. He completed his medical school training and residency at the University of Texas Southwestern Medical Center in Dallas. He subsequently completed his gastroenterology fellowship at Northwestern University, Feinberg School of Medicine, and then completed a two-year interventional endoscopy fellowship at Northwestern University, with a focus on pancreaticobiliary disorders, ERCP, EUS and complex esophageal disease. Prior to joining the Mass General Division of Gastroenterology, Dr. Krishnan was an interventional endoscopist at the Houston Methodist Hospital, where he established the interventional endoscopy program.

Dr. Krishnan currently serves on the American Society for Gastrointestinal Endoscopy (ASGE) Technology Committee and on the editorial board for Video Gastrointestinal Endoscopy. He is a reviewer for the American Journal of Gastroenterology, Gastrointestinal Endoscopy, Alimentary Pharmaceutical and Therapeutics and Diseases of the Esophagus. His primary clinical interests include the management of pancreatic and biliary disease, interventional endoscopy and novel endoscopic therapy for digestive disease. He is actively involved in research relating to novel diagnostic and therapeutic technology in endoscopy and minimally invasive treatments for intestinal disorders.

Advanced Practice Providers

Alexandra Maltby is a physician assistant in the Division of General Surgery and Acute Care Surgery and Heartburn and Reflux Program at Newton-Wellesley Hospital. She also practices at the Mass General SHED Center. She earned her Bachelor of Science in Biology with a concentration in Neuroscience from Emmanuel College and received her Master’s in Physician Assistant Studies from Bay Path University in 2017.

Priyanca Waghmarae is a physician assistant at the Mass General Department of Gastroenterology. She works with the Mass General SHED Center, caring for patients with foregut disease, and with the Mass General pancreatic and biliary interventional team. Priyanca earned her Bachelor of Science in Biomedical Studies with a minor in Psychology from Rochester Institute of Technology in 2014 and her Master's in Physician Assistant Studies at Daeman College in 2017.

We will expand page to include keynote speakers and additional faculty, as they’re confirmed.


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Video Introduction to MINT 2021

In this video, course directors, Charudutt Paranjape, MD, MBBS, and Kumar Krishnan, MD, introduce the MINT CME.

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Registration and Pricing

We are offering Early Bird pricing through July 1, 2022.


Virtual, no CME credit

  • Physicians and APPs—free

Virtual, CME credit

  • Physicians—$150 early bird or $200 regular
  • International—$100 early bird or $150 regular
  • APPs—$100 early bird or $150 regular

In-Person, CME credit

  • Physicians—$250 early bird or $300 regular
  • International—$200 early bird or $250 regular
  • APPs and students—$100 early bird or $150 regular
  • Residents and fellows—$100 early bird or $150 regular

In-Person, hands-on course (limited spots)

  • Physicians—$200 early bird or $250 regular


  • Industry representative—$300

How to Register

Click here to register for the course.