Posts by Deborah J. Wexler, MD, MSc
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Psychological and Behavioral Factors Identified That Predict Success of Lifestyle Interventions for Weight Loss
Massachusetts General Hospital researchers identified improvements in autonomous motivation, dietary self-regulation, and low-fat diet as the most important predictors of weight loss during a two-year lifestyle intervention, but only improvements in low-fat diet and depression were important after a year of follow-up.
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Study Positions SGLT2 Inhibitors as Gout Treatment
A Massachusetts General Hospital research team has found that SGLT2 inhibitor therapy reduces gout flares and lowers the risk of myocardial infarction in patients with diabetes.
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Medical Grand Rounds: Results of the Glycemia Reduction Approaches in Diabetes Study
In a recent Medical Grand Rounds presentation, the Endocrine Division at Massachusetts General Hospital presented major results of the Glycemia Reduction Approaches in Diabetes—A Comparative Effectiveness (GRADE) study, designed to help guide the choice of glucose-lowering medications added to metformin.
Biography
Deborah J. Wexler, MD, MSc, is Associate Professor of Medicine at Harvard Medical School, Boston, Massachusetts, the Chief of the Massachusetts General Hospital Diabetes Unit, and Clinical Director of the Mass General Diabetes Center. She received her medical degree from Yale University School of Medicine, New Haven, Connecticut, her MSc from the University of Oxford, and completed her internship, residency, and chief residency in internal medicine and fellowship in endocrinology at Massachusetts General Hospital.
Dr. Wexler’s research focuses on clinical effectiveness in type 2 diabetes. She is the MGH site Principal Investigator and is on the Executive Committee of the GRADE Study, a NIH-funded multicenter trial to determine which second hypoglycemic drug, added to metformin, is most effective for patients with type 2 diabetes (http://gradestudy.com/). She is also multiple-Principal Investigator of the REAL HEALTH-Diabetes trial, which is translating the Look AHEAD lifestyle intervention for type 2 diabetes into usual care at community health centers. She served on the American Diabetes Association’s Professional Practice Committee (2014-2016) and was a co-author of the ADA-EASD position statement on management of hyperglycemia in type 2 diabetes. Dr Wexler is on the Editorial Board of Diabetes Care and is a reviewer for multiple medical journals.
Endocrinology Division
The Endocrinology Division at Massachusetts General Hospital offers a comprehensive integrated program of clinical services for both primary and tertiary care of adults with endocrine disorders.