Posts by Wolfram Goessling, MD, PhD
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Embryonic Alcohol Exposure Disrupts the Ubiquitin–Proteasome System
Wolfram Goessling, MD, PhD, Olivia Weeks, PhD, and colleagues provide evidence from a zebrafish model that alcohol exposure disrupts protein homeostasis during fetal development, and abnormal function of the ubiquitin-proteasome system can contribute to the development of fetal alcohol spectrum disorders.
Biography
Dr. Wolfram Goessling is the Chief of Mass General Gastroenterology where he holds the Jules L. Dienstag, MD and Betty and Newell Hale Endowed Chair in Gastroenterology. He also serves as the Robert H. Ebert Professor of Medicine at Harvard Medical School and the Director of the Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology at HMS. After earning his MD and PhD from the University of Witten/Herdecke Medical School in Germany, Dr. Goessling completed his residency training in Internal Medicine at the Brigham and Women’s Hospital at Harvard Medical School, where he also served as Chief Medical Resident. Dr. Goessling then pursued fellowship training in Hematology/Oncology at the Dana-Farber/Mass General Brigham Cancer Care Fellowship Program, and in Gastroenterology at the Massachusetts General Hospital.
He is trained in both oncology and gastroenterology, and maintains a clinical practice focused on the treatment of patients with chronic liver disease and liver cancer. He actively teaches medical students as Director of the Introduction to Clinical Medicine course, and graduate students in the Developmental and Regenerative Biology program at Harvard Medical School. Dr. Goessling is a physician-scientist, and his laboratory investigates molecular signals that regulate liver growth and metabolism during liver development, regeneration, and liver cancer formation.
Digestive Healthcare at Mass General
The Massachusetts General Hospital Digestive Healthcare Center is a collaborative practice of gastroenterologists, endoscopists, surgeons, radiologists, pathologists, hepatologists, oncologists and radiation oncologists dedicated to the prevention, diagnosis, treatment and management of digestive diseases.