Posts by Alessio Fasano, MD
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Life-threatening COVID-19–Related Disease of Children Driven by Loss of Gut Barrier
Massachusetts General Hospital and Brigham and Women's researchers have provided evidence that gastrointestinal sources of SARS-CoV-2 antigens may instigate and drive multisystem inflammatory syndrome in children, the life-threatening immune activation syndrome associated with prior SARS-CoV-2 infection or exposure.
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Intestinal Organoids Expressing Celiac Disease Respond Differently to Gluten Exposure
A study co-authored by researchers at Massachusetts General Hospital validated the organoid model for celiac disease research.
Biography
World-renowned pediatric gastroenterologist, research scientist and entreprenuer Dr. Alessio Fasano is chief of Pediatric Gastroenterology and Nutrition at Mass General for Children (MGfC). Dr. Fasano directs the Center for Celiac Research, specializing in the treatment of patients of all ages with gluten-related disorders, including celiac disease, wheat allergy and gluten sensitivity. He treats patients with acute and chronic diarrheal diseases, and treats infants and children who have difficult-to-treat gastrointestinal problems.
Dr. Fasano also directs the Mucosal Immunology and Biology Research Center and is associate chief for Basic, Clinical and Translational Research. Under his leadership, investigators are studying the molecular mechanisms of autoimmune disorders including celiac disease, and other-gluten-related disorders. He has been named visiting professor of pediatrics at Harvard Medical School. He authored the groundbreaking study in 2003 that established the rate of celiac disease at one in 133 Americans. Widely sought after by national and international media, Dr. Fasano has been featured in hundreds of interviews including outlets such as The New York Times, The Wall Street Journal; National Public Radio; CNN; Bloomberg News, and others.
Digestive Healthcare at Mass General
The Massachusetts General Hospital Digestive Healthcare Center is a collaborative practice of gastroenterologists, endoscopists, surgeons, radiologists, pathologists, hepatologists, oncologists and radiation oncologists dedicated to the prevention, diagnosis, treatment and management of digestive diseases.