Posts by Nancy J. Donovan, MD
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Brain Pathology Adds to Evidence of Link Between Social Activity and Preserved Cognition in Older Adults
Heidi I. L. Jacobs, PhD, and colleagues determined the greater density of tau tangles in the locus coeruleus may degrade cognition and social function independently of Alzheimer's disease pathology and before the onset of cognitive impairment. And that the amount of social activity can partially explain this.
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Larger Study Confirms Loneliness as a Preclinical Symptom of Alzheimer's Disease
Researchers previously reported that in cognitively normal older adults, loneliness scores were associated with greater cortical deposition of amyloid-β. These findings have now been confirmed in a larger study that also involved imaging of tau.