-
Featured
Mindfulness-based Cognitive Therapy Shows Promise for Treating Depression in Chronically Ill Patients
Mass General researchers were part of the first group to investigate whether mindfulness-based cognitive therapy might relieve depression in people with chronic pain.
-
Featured
Women with Major Depression During Pregnancy Have High Rates of Recurrence During Their Child's Formative Years
Depression during pregnancy is highly likely to recur after delivery, Mass General researchers have determined. The finding implies that maternal depression is a major confounder when assessing the influence of prenatal antidepressant exposure on child neurodevelopment.
-
Featured
Effective Ketamine Dosages for Treatment-resistant Depression Identified
Ketamine has long been used as a general anesthetic, but more recent research has found it to be effective in rapidly relieving depression symptoms when given at low, subanesthetic doses. New research identifies two optimal dosages.
-
Heated Yoga Linked to Reduction of Moderate to Severe Depressive Symptoms in Randomized Controlled Trial
In 2021, a randomized controlled trial showed heated yoga outperformed a waitlist control in a group of women with mild-to-moderate depression. Researchers at Massachusetts General Hospital have extended the findings to a larger, mixed-gender, and more severely depressed population.
-
Genetic Factors May Substantially Account for Associations Between Screen Time and Psychiatric Problems in Preadolescents
Massachusetts General Hospital psychologist Karmel W. Choi, PhD, and colleagues found genetic confounding, modeled with polygenic risk scores and heritability, accounted for 10% of the link between child screen time and attention problems and 43% of the link between screen time and internalizing problems.
-
Pain Catastrophizing Is Associated With Reduced Neural Response to Monetary Reward
Megan E. Cooke, PhD, Jodi M. Gilman, PhD, and colleagues present evidence that higher levels of pain catastrophizing are associated with decreased activation to monetary reward in the striatum, beyond the influence of more general affective factors such as comorbid depression symptoms.
Depression Contributors
-
Cristina Cusin, MD
Assistant Professor in Psychiatry, Staff Psychiatrist, Depression Clinical and Research Program
Recent Article
Q&A with Dr. Cristina Cusin: What to Know About Esketamine and Ketamine Treatment -
David Mischoulon, MD, PhD
Director, Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Joyce R. Tedlow Professor of Psychiatry, Harvard Medical School
Recent Article
Heated Yoga Linked to Reduction of Moderate to Severe Depressive Symptoms in Randomized Controlled Trial -
Maurizio Fava, MD
Psychiatrist-In-Chief; Director, Division of Clinical Research of the MGH Research Institute, Executive Director, Clinical Trials Network and Institute (CTNI), Massachusetts General Hospital, Associate Dean for Clinical & Translational Research, Slater Family Professor of Psychiatry, Harvard Medical School
Recent Article
AI Approach Can Predict Placebo Responders in Clinical Trials in Major Depressive Disorder