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Featured
Sex-specific Genetic Effects Across Neuropsychiatric and Behavioral Traits Identified for the First Time
Jill M. Goldstein, PhD, and Jordan W. Smoller, MD, ScD, of the Department of Psychiatry, and colleagues have reported the first modest evidence of sex-dependent autosomal genetic effects across neuropsychiatric and behavioral traits.
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Featured
Longitudinal Data in Electronic Health Records Can Be Used to Predict Risk of Suicide
Previous research has shown that diagnostic codes routinely collected in electronic health records can help predict domestic abuse an average of two years in advance. Could EHR systems also be used to predict suicidal behavior?
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Mind–Body Intervention for Chronic Pain Benefits Adults 50 and Older
Massachusetts General Hospital researchers provide novel evidence that adults ages 50 and older with chronic pain benefit from a mind–body program designed to increase physical function—and show even greater benefits in pain and performance-based physical function than younger adults.
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Artificial Intelligence Promising As a Decision Support Tool When Treating Bipolar Depression
Roy H. Perlis, MD, MSc, and colleagues have demonstrated the potential utility of prompting GPT-4 with treatment guidelines for bipolar depression. The artificial intelligence model showed modest agreement with experts—and better performance than community physicians—in selecting the optimal next-step medication.
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New Website Allows Provider Consultations for Patients With Restless Leg Syndrome
A new online forum educates healthcare providers about restless leg syndrome augmentation, risks of treatment with ropinirole or pramipexole, and treatment alternatives.
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Uncovering the Relationship Between Loneliness and Poor Health Outcomes
In an ongoing project, Mass General researchers are studying the epidemic of worsening loneliness and social isolation and its relationship to poor health outcomes. They have identified a potential marker of loneliness, which could help understand the effects of loneliness on the body and even how to reverse them.
Psychiatry Contributors
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David Mischoulon, MD, PhD
Director, Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Joyce R. Tedlow Professor of Psychiatry, Harvard Medical School
Recent Article
Heated Yoga Linked to Reduction of Moderate to Severe Depressive Symptoms in Randomized Controlled Trial -
Eve Valera, PhD
Researcher, Athinoula A. Martinos Center for Biomedical Imaging
Recent Article
Q&A: Dr. Eve Valera on Intimate Partner Violence and Brain Injury -
Jodi Gilman, PhD
Director of Neuroscience, Center for Addiction Medicine, Massachusetts General Hospital
Recent Article
Pain Catastrophizing Is Associated With Reduced Neural Response to Monetary Reward -
Jordan W. Smoller, MD, ScD
Associate Chief for Research, Department of Psychiatry, Massachusetts General Hospital, Director, Psychiatric and Neurodevelopmental Genetics Unit, Professor of Psychiatry at Harvard Medical School and Professor in the Department of Epidemiology at the Harvard School of Public Health
Recent Article
Psychiatric Disorders Not Associated With Incidental Findings in Medically Actionable Genes -
Maurizio Fava, MD
Psychiatrist-In-Chief; Director, Division of Clinical Research of the MGH Research Institute, Executive Director, Clinical Trials Network and Institute (CTNI), Massachusetts General Hospital, Associate Dean for Clinical & Translational Research, Slater Family Professor of Psychiatry, Harvard Medical School
Recent Article
AI Approach Can Predict Placebo Responders in Clinical Trials in Major Depressive Disorder