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Featured
Review: Pathways of Colorectal Carcinogenesis
Dozens of different somatic mutations have been identified in colorectal tumors, but colorectal cancer appears to develop via one of only a few distinct pathways.
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Featured
Review: Lifestyle Factors, Changes in Gut Microbiota Are Linked in Development of Colorectal Cancer
Both diet, lifestyle and the gut microbiome have been implicated in colorectal tumorigenesis. Accumulating evidence suggests these two influences are related and may point the way to better prevention strategies.
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Featured
Fiber Intake Has Survival Benefit in Patients Already Diagnosed with Colorectal Cancer
In the first prospective study of the topic, gastroenterologists and epidemiologists at Massachusetts General Hospital found that higher fiber intake after a diagnosis of nonmetastatic colorectal cancer is associated with longer survival.
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Mortality Risk Significantly Greater With Interval CRC Than Screen-detected CRC
Keming Yang, MD, PhD, Andrew T. Chan, MD, MPH, and colleagues detected significantly increased mortality for individuals with interval colorectal cancer (CRC) than for those with screen-detected CRC, and differences in established clinical prognostic factors, genetic characteristics, could not explain the discrepancy.
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Initiating Screening Before Age 50 Reduces Risk of Colorectal Cancer
Researchers at Massachusetts General Hospital found that starting endoscopic screening before age 50 is associated with a greater reduction in the absolute risk of colorectal cancer compared with starting at later ages. The data support national recommendations to start screening at age 45 for average-risk individuals.
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No Link Between Gluten Intake, Digestive System Cancers in People Without Celiac Disease
By analyzing data from three large U.S. longitudinal cohorts, Massachusetts General Hospital researchers found individuals without celiac disease are unlikely to reduce their risk of digestive system cancers by following a low-gluten or gluten-free diet.
Mass General Cancer Center Contributors
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Daniel C. Chung, MD
Clinical Chief, Gastrointestinal Unit, Director, High-Risk GI Cancer Clinic
Recent Article
Pilot Study: Virtual Reality Is a Feasible Alternative to Narcotics During Colonoscopy
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David L. Berger, MD
Colorectal and Gastrointestinal Surgeon, Massachusetts General Hospital Division of General Surgery, Associate Professor of Surgery, Harvard Medical School
Recent Article
Primary Tumor Resection Improves Survival in Advanced Colorectal Cancer
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Hiroko Kunitake, MD, MPH
Colorectal Surgeon, Center for Pelvic Floor Disorders, Massachusetts General Hospital, Assistant Professor of Surgery, Harvard Medical School
Recent Article
New Research Further Quantifies Benefits of Preventative Colonoscopy Screening -
Liliana G. Bordeianou, MD, MPH, FACS, FASCRS
Site Director of the Colorectal Surgery Program, Co-Director, Pelvic Floor Disorders Center, Mass General, Co-Chair, Mass General Brigham Colorectal Surgery Collaborative, Professor of Surgery, Harvard Medical School
Recent Article
New Scoring System Allows Assessment of the Severity of Ileoanal Pouch Syndrome
Mass General Cancer Center
An integral part of one of the world’s most distinguished academic medical centers, the Massachusetts General Hospital Cancer Center is among the leading cancer care providers in the United States.
