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Featured
Tau PET Imaging May Help Identify People with Pre-symptomatic Alzheimer’s Disease
Brain changes associated with Alzheimer’s disease can now be studied in living people. Mass General researchers imaged cognitively normal people who are destined to develop AD due to a rare genetic mutation. Their goal: to discover how soon brain changes are present before symptoms begin and how soon preventive treatments could be initiated.
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Featured
NEJM Images in Clinical Medicine: Using Ventriculoperitoneal Shunt Placement to Treat Normal-pressure Hydrocephalus
Neurologists at Mass General explore the case of a woman who endured gait disturbance, cognitive impairment and urinary incontinence for 2 years before she was diagnosed with normal-pressure hydrocephalus and successfully treated with surgical shunting.
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Featured
fMRI and EEG May Find Signals of Consciousness Earlier in Severe Traumatic Brain Injury Patients
The rate of misclassification of unconsciousness can be as high as 40%. A Mass General team studied using fMRI and EEG to better identify patients with unconsciousness in the ICU.
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Human Stem Cell-derived Organoids Facilitates Research into ALS Pathogenesis, Therapy
Using stem cells generated from patients with amyotrophic lateral sclerosis (ALS), João D. Pereira, PhD, and Brian J. Wainger, MD, PhD, of the Healey Center for ALS, and colleagues derived sensorimotor organoids that contain functional neuromuscular junctions and applied the model to different subgroups of ALS.
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Tau Pathobiology Differs Among Individuals with Alzheimer's Disease
Researchers at Massachusetts General Hospital observed differences in the kinetics of tau aggregation across brain tissue samples from individuals with sporadic Alzheimer's disease, confirming and extending the concept of patient-specific characteristics of tau in this disease.
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Extrapial Hippocampal Resection in Anterior Temporal Lobectomy for Drug-Resistant Temporal Lobe Epilepsy
Mark Richardson, MD, PhD, of the Department of Neurosurgery, and colleagues describe an extrapial approach to hippocampal resection in anterior temporal lobectomy for treatment of drug-resistant temporal lobe epilepsy that has proven to be safe and as effective as subpial techniques.
Neurology Contributors
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Brian L. Edlow, MD
Associate Director, Center for Neurotechnology and Neurorecovery (CNTR), Director, Laboratory for NeuroImaging of Coma and Consciousness (NICC), Director, Critical Care Research Neuroimaging
Recent Article
Functional MRI Detects Intact Brain Network in Patient Unresponsive After COVID-19
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Jodi Gilman, PhD
Director of Neuroscience, Center for Addiction Medicine, Massachusetts General Hospital
Recent Article
Portable Imaging Test Shows Promise for Detection of Cannabis Intoxication
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Keith A. Johnson, MD
Radiologist
Recent Article
Tau PET Imaging May Help Identify People with Pre-symptomatic Alzheimer’s Disease
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Nagagopal Venna, MD
Director, Neurology Clinic, Director, Neuro-Infectious Diseases Clinic, Director, Academic General Neurology Fellowship Program
Recent Article
NEJM Images in Clinical Medicine: Using Ventriculoperitoneal Shunt Placement to Treat Normal-pressure Hydrocephalus
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Yakeel T. Quiroz-Gaviria, PhD
Associate Professor, Harvard Medical School, Director, Familial Dementia Neuroimaging Lab, Director, Multicultural Alzheimer's Prevention Program, Massachusetts General Hospital, Paul B. and Sandra M. Edgerley MGH Research Scholar 2020-2025
Recent Article
Retinal Imaging Detects Biomarkers of Familial Alzheimer's Disease Years Before Symptoms
Neuroscience Care at Mass General
Through a combination of unmatched expertise, creativity and compassion, Mass General Neuroscience relentlessly advances the fields of Neurosurgery, Neurology and Psychiatry to unleash our patients’ potential.Resource Links
