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Featured
Sex-specific Genetic Effects Across Neuropsychiatric and Behavioral Traits Identified for the First Time
Jill M. Goldstein, PhD, and Jordan W. Smoller, MD, ScD, of the Department of Psychiatry, and colleagues have reported the first modest evidence of sex-dependent autosomal genetic effects across neuropsychiatric and behavioral traits.
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Featured
Longitudinal Data in Electronic Health Records Can Be Used to Predict Risk of Suicide
Previous research has shown that diagnostic codes routinely collected in electronic health records can help predict domestic abuse an average of two years in advance. Could EHR systems also be used to predict suicidal behavior?
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Uncovering the Relationship Between Loneliness and Poor Health Outcomes
In an ongoing project, Mass General researchers are studying the epidemic of worsening loneliness and social isolation and its relationship to poor health outcomes. They have identified a potential marker of loneliness, which could help understand the effects of loneliness on the body and even how to reverse them.
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Heated Yoga Linked to Reduction of Moderate to Severe Depressive Symptoms in Randomized Controlled Trial
In 2021, a randomized controlled trial showed heated yoga outperformed a waitlist control in a group of women with mild-to-moderate depression. Researchers at Massachusetts General Hospital have extended the findings to a larger, mixed-gender, and more severely depressed population.
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Genetic Factors May Substantially Account for Associations Between Screen Time and Psychiatric Problems in Preadolescents
Massachusetts General Hospital psychologist Karmel W. Choi, PhD, and colleagues found genetic confounding, modeled with polygenic risk scores and heritability, accounted for 10% of the link between child screen time and attention problems and 43% of the link between screen time and internalizing problems.
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Pain Catastrophizing Is Associated With Reduced Neural Response to Monetary Reward
Megan E. Cooke, PhD, Jodi M. Gilman, PhD, and colleagues present evidence that higher levels of pain catastrophizing are associated with decreased activation to monetary reward in the striatum, beyond the influence of more general affective factors such as comorbid depression symptoms.
Psychiatry Contributors
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David Mischoulon, MD, PhD
Director, Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Joyce R. Tedlow Professor of Psychiatry, Harvard Medical School
Recent Article
Heated Yoga Linked to Reduction of Moderate to Severe Depressive Symptoms in Randomized Controlled Trial -
Eve Valera, PhD
Researcher, Athinoula A. Martinos Center for Biomedical Imaging
Recent Article
Q&A: Dr. Eve Valera on Intimate Partner Violence and Brain Injury -
Jodi Gilman, PhD
Director of Neuroscience, Center for Addiction Medicine, Massachusetts General Hospital
Recent Article
Pain Catastrophizing Is Associated With Reduced Neural Response to Monetary Reward -
Jordan W. Smoller, MD, ScD
Associate Chief for Research, Department of Psychiatry, Massachusetts General Hospital, Director, Psychiatric and Neurodevelopmental Genetics Unit, Professor of Psychiatry at Harvard Medical School and Professor in the Department of Epidemiology at the Harvard School of Public Health
Recent Article
Psychiatric Disorders Not Associated With Incidental Findings in Medically Actionable Genes -
Maurizio Fava, MD
Psychiatrist-In-Chief; Director, Division of Clinical Research of the MGH Research Institute, Executive Director, Clinical Trials Network and Institute (CTNI), Massachusetts General Hospital, Associate Dean for Clinical & Translational Research, Slater Family Professor of Psychiatry, Harvard Medical School
Recent Article
AI Approach Can Predict Placebo Responders in Clinical Trials in Major Depressive Disorder