Specialty Neuroscience
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Featured
Closing the Health Equity Gap in Neurosurgical Care
Neurosurgeon Theresa Williamson, MD, a Massachusetts General Hospital physician-scientist and medical ethicist, studies decision-making and health care disparities in neurosurgery.
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Featured
Mass General Renews Focus on Pediatric Epilepsy
A new team approach at Mass General is applying advances in adult epileptics, such as epilepsy surgery and responsive neurostimulation, to children.
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Lessons for Developing Polygenic Risk Scores With Multi-Ancestry Genome-wide Association Studies
Ying Wang, PhD, Alicia R. Martin, PhD, and colleagues discuss lessons learned and guidelines for best practices after developing polygenic risk scores with multi-ancestry genome-wide association studies for 14 disease endpoints across nine biobanks.
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Optimal Deep Brain Stimulation Sites and Networks for Stimulation of the Fornix in Alzheimer's Disease
Andreas Horn, PhD, MD, and colleagues have reported a potentially optimal stimulation target for deep brain stimulation to the fornix for patients with Alzheimer's disease. Their findings will allow refinement of clinical trials to answer whether this treatment could be effective for more patients.
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Targeting Lipid Synthesis Efficacious in Glioblastoma Mouse Models
Katharina M. Eyme, Alessandro Sammarco, PhD, Christian E. Badr, PhD, and colleagues found YTX-7739, an orally available stearoyl coenzyme A desaturase 1 inhibitor, triggered lipotoxicity in glioblastoma stem-like cells, and with or without temozolomide, it was efficacious in mouse models of glioblastoma.
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Diminished Frontal Pole Size, Functional Connectivity Linked to Elevated Suicide Risk in Young Adults
Gwang-Won Kim, PhD, Maurizio Fava, MD, Daphne J. Holt, MD, PhD, and colleagues published evidence that reduced frontal pole size and reduced functional connectivity between the frontal pole and the inferior frontal cortex are markers of elevated suicidality in young adults.
Neuroscience Contributors
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Aman B. Patel, MD
Director of Cerebrovascular and Endovascular Neurosurgery, Co-Director of the Neuroendovascular Program
Recent Article
No Sex Differences in Outcomes After Endovascular Thrombectomy for LVO Stroke
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Bob S. Carter, MD, PhD
Chief, Neurosurgery Service
Recent Article
The Future of Neurosurgery and Neuroscience at Mass General: Q&A With Bob S. Carter, MD, PhD
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Ghazaleh Sadri-Vakili, MS, PhD
Assistant in Neuroscience, Massachusetts General Hospital, Assistant Professor of Neurology, Harvard Medical School
Recent Article
Novel Target Identified for Treatment of ALS
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Jill M. Goldstein, PhD
Founder & Executive Director, Innovation Center on Sex Differences in Medicine, Massachusetts General Hospital, Helen T. Moerschner Endowed MGH Research Institute Chair in Women’s Health, Professor of Psychiatry & Medicine, Harvard Medical School
Recent Article
Novel Form of Vagus Nerve Stimulation Promising for Treatment of Major Depressive Disorder
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Jordan W. Smoller, MD, ScD
Associate Chief for Research, Department of Psychiatry, Massachusetts General Hospital, Director, Psychiatric and Neurodevelopmental Genetics Unit, Professor of Psychiatry at Harvard Medical School and Professor in the Department of Epidemiology at the Harvard School of Public Health
Recent Article
Psychiatric Disorders Not Associated With Incidental Findings in Medically Actionable Genes
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Maurizio Fava, MD
Psychiatrist-In-Chief; Director, Division of Clinical Research of the MGH Research Institute, Executive Director, Clinical Trials Network and Institute (CTNI), Massachusetts General Hospital, Associate Dean for Clinical & Translational Research, Slater Family Professor of Psychiatry, Harvard Medical School
Recent Article
Diminished Frontal Pole Size, Functional Connectivity Linked to Elevated Suicide Risk in Young Adults
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Merit Ester Cudkowicz, MD, MSc
Chief, Neurology Service, Director of the Sean M. Healey & AMG Center for ALS at Mass General, Director of Neurological Clinical Research Institute and the Jilieane Dorn Professor of Neurology, Harvard Medical School
Recent Article
Tofersen Lowers Disease Markers, Slowing Progression for SOD1-Mutated ALS in Phase 3 Trial
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Natalia S. Rost, MD, MPH, FAAN
Chief of Stroke Division, Department of Neurology, Massachusetts General Hospital, Professor of Neurology, Harvard Medical School
Recent Article
Multiple Lesions Are More Frequent Than Previously Thought in Acute Ischemic Stroke
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Rudolph E. Tanzi, PhD
Joseph P. and Rose F. Kennedy Professor of Neurology, Harvard Medical School, Vice-Chair, Massachusetts General Hospital Neurology Department, Co-Director of the McCance Center for Brain Health, Massachusetts General Hospital
Recent Article
How Amyloid-beta Forms Suggests New Strategies for Preventing, Treating Alzheimer's Disease
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Timothy Wilens, MD
Chief, Division of Child and Adolescent Psychiatry, Massachusetts General Hospital, Co-director, Center for Addiction Medicine, Director, Substance Abuse Services in Pediatric Psychopharmacology
Recent Article
Treatment for Substance Use Disorder Reduces Risk of Overdose in Young Adults
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William T. Curry, MD
Co-Director, Mass General Neuroscience , Director of Neurosurgical Oncology, Massachusetts General Hospital, Adeline Rose Wydotis Professor of Neurosurgery, Harvard Medical School
Recent Article
Designing Leading-Edge Immunotherapy for Brain Cancer
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Ziv Williams, MD
Neurosurgeon, Department of Neurosurgery, Massachusetts General Hospital, Associate Professor in Neurosurgery, Harvard Medical School
Recent Article
Basic Rules Identified for Therapeutic Intracranial Stimulation of the Human Brain
Neuroscience Care at Mass General
Through a combination of unmatched expertise, creativity and compassion, Mass General Neuroscience relentlessly advances the fields of Neurosurgery, Neurology and Psychiatry to unleash our patients’ potential.