Posts by Siam Oottamasathien, MD
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Interstitial Cystitis Research and Therapeutics to Treat Radiation-induced Proctitis
Siam Oottamasathien, MD, is the director of Pediatric Urology Basic Science Research at Massachusetts General Hospital. In this video, he discusses his research on interstitial cystitis, also known as painful bladder syndrome, and treatment of radiation-induced proctitis.
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Enhanced Delivery System Improves Dwell Time of Drug for Interstitial Cystitis
A synthetic glycosaminoglycan, when combined with a novel polymer for enhanced intravesical delivery, was released in the bladders of mice for 24 hours, leading to reduced abdominal pain and inflammation.
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Advances in the Pathophysiology, Potential Treatment of Interstitial Cystitis
Using a mouse model of interstitial cystitis, researchers have newly identified an IL-33/mast cell axis in the bladder, suggesting how novel treatments might be developed for this painful, debilitating condition.